Impact of lipid Profile on Creatine kinase-MB in Myocardial Infarction Patients

Abstract

Myocardial necrosis results from a sudden stoppage of the coronary blood flow to a portion of the myocardium, and it is referred to as a myocardial infarction (MI). MI is almost caused by atherosclerosis. The goal of this study was to determine the extent to which certain lipid profile parameters caused the increase in creatine kinase-MB (CK-MB) levels, and both are positively correlated with mortality and Myocardial infarction (MI) patients.

This study was carried out between December 2021 and March 2022. The 60 myocardial infarction patients were compared to the outcomes of 40 healthy individuals included 20 males and 20 females with matched ages Diyala Governate. Serum CK-MB values from the time of admission were used to gauge the extent of myocardium injury; and using fasting blood samples, lipid profile was estimated. Data analysis was performed using statistical tool SPSS Roc curve. The findings of this study revealed a substantial positive association between triacylglycerol (TG), very-low-density lipoprotein (VLDL), and total cholesterol (TC), but a negative correlation between HDL and CK-MB levels. The results of the study showed that TG, VLDL, LDL, and TC significantly impacted the severity of the myocardial damage in the patients. According to this study, social determinants of health play a role in the regional difference in cardiovascular illnesses. Results were much greater and exhibited an inverse among the less educated. In order to assess the diagnostic utility of lipid profile ratio and CK-MB ratio for determining the severity of myocardial infarction (MI).