Study the Serum Complement C3, C4 and Some Hematology Parameters in COVID-19 Disease

Abstract

The COVID-19 pandemic has become a real challenge to the medical community. Along with the problem of treating patients in critical conditions caused by SARS-CoV-2, the pandemic COVID-19 has exacerbated some environmental, social and biomedical problems.This research included 90 patients with COVID-19 and 30 non-infected (positive control). All samples were collected from nasal swabs and pharyngeal swabs in subjects of different ages and gender from the period November 2021 to February 2022 and was performed at Baqubah General Hospital in Diyala. All samples (from infected patients and healthy patients) were already identified by using Reverse Transcriptase Polymerase Chain Reaction (RT-PCR). Complement C3, C4 and white blood cells, lymphocytes and platelets were determined for all samples. The current study indicates that the COVID-19 patients showed lower levels of C3 and C4 were (96.48 ± 6.72 and 22.03 ± 1.67) mg/dl respectively, while the hematology tests showed a lesser ratio of WBC and LYM were (11.94 ± 0.73 and 20.35 ± 1.46) µl, while a high ratio of PLT was (288.71 ± 12.71) µl.