Application of Radioimmunoassay Technology for the Detection of Thyroid Disorder Among Diabetic Patients
DOI:
https://doi.org/10.24237/04.02.817Abstract
Over 200 million people worldwide are affected by type 2 diabetes mellitus (DM), according to research Sub-clinical hypothyroidism in diabetic individuals has been linked to an increased risk of cardiovascular disease and nephropathy. The aim of this study is to assess thyroid dysfunction in hypoglycemic patients with type 2 diabetes through comprehensive evaluation of thyroid hormone profiles using radioimmunoassay technology.This study divided in two groups firstly carried 40 patients with tybe2 diabetes mellitus were included in this study age range (40-60) years, a full clinical estimation was applied for all patients including physical examinations, and history of disease. Second group involved 40 healthy volunteers age range (40-60) years included in this present study as control.. All the patients were euthyroid, and there are no clinically significant cases of hypothyroidism or hyperthyroidism. The mean of total and free tri-iodothyroxine levels was significantly lower in patients with type 2 DM (1.19 ± 0.292, 3.24 ± 1.13, respectively) than in the control group (1.58 ± 0.33, 4.73 ± 0.99, respectively), and the difference was statistically significant (p < 0.003, p < 0.001, respectively), while total and free thyroxine and thyrotropin showed no statistically significant difference. Thyroid hormone abnormalities are common in DM type 2 patients, euthyroid was more common among patients with hypoglycemia than hyperthyroidism and hypothyroidism, So, regular screening for thyroid hormone abnormalities in DM2 will allow early treatment of subclinical thyroid abnormalities.
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